Product Details
Place of Origin: China
Document: Product Brochure PDF
Payment & Shipping Terms
Minimum Order Quantity: 100Grams
Price: USD
Packaging Details: 1kg/Foil Bag
Delivery Time: 3-7days after received payment
Payment Terms: T/T, Western Union,PayPal
Supply Ability: 5000KG Per Year
Product Name: |
Orlistat |
CAS: |
96829-58-2 |
Appearance: |
White Powder |
Purity: |
98% |
Use For: |
Weight Loss |
Product Name: |
Orlistat |
CAS: |
96829-58-2 |
Appearance: |
White Powder |
Purity: |
98% |
Use For: |
Weight Loss |
Weight Loss Powder Orlistat CAS 96829-58-2 Treating Obesity Slimming
Quick detail
| Product Name: | Orlistat |
| Synonyms: | (S)-2-FORMYLAMINO-4-METHYL-PENTANOIC ACID (S)-1-[[(2S,3S)-3-HEXYL-4-OXO-2-OXETANYL]METHYL]-DODECYL ESTER;RO-18-0647;(-)-TETRAHYDROLIPSTATIN;ORLISTAT;N-FORMYL-L-LEUCINE (1S)-1-[[(2S,3S)-3-HEXYL-4-OXO-2-OXETANYL]METHYL]DODECYL ESTER;XENICAL;(-)-Tetrahydrolipstatin(EquivalentToOrlistat);Orlipastat |
| CAS: | 96829-58-2 |
| MF: | C29H53NO5 |
| MW: | 495.73 |
| Product Categories: | Pharmaceutical Raw Materials;Miscellaneous Biochemicals;API;Antiobesity Agent;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Amino Acids & Derivatives;Heterocycles;ACTOS;Other APIs;Lipid-lowering medicine reducing weight |
Orlistat Usage
| Usage | An antiobesity agent. A pancreatic lipase inhibitor. Antiobesity agent. |
| Usage | antidiabetic |
| Usage | Orlistat is an antiobesity agent. Orlistat is an pancreatic lipase inhibitor. |
| Usage | Tetrahydrolipstatin (orlistat) is a semi-synthetic derivative of lipstatin, a metabolite isolated from Streptomyces toxytricini. Tetrahydrolipstatin acts as a potent, irreversible inhibitor of pancreatic lipase. In vivo, it blocks the absorption of triglycerides while allowing fatty acid absorption. Tetrahydrolipstatin is widely used for the treatment of obesity. |
| Biological Activity | Hypolipemic pancreatic, gastric and carboxylester lipase inhibitor. Exhibits no activity at phospholipase A 2 , liver esterase, trypsin and chymotrypsin. Inhibits the thioesterase domain of fatty acid synthase, leading to cell cycle arrest at the G 1 /S boundary in vitro . Prevents the absorption of approximately one third of fat from food and exhibits progastrokinetic, antiobesity and antihypercholesterolemic activity in vivo . |
Applications:
| 1. | Orlistat is a drug that promotes loss of weight by preventing the digestion and absorption of fat in food. In the intestine, an enzyme called lipase (produced primarily by the pancreas) breaks apart fat in food so that it can be absorbed into the body. |
| 2. | Orlistat blocks the action of lipase and thereby prevents the breakup and absorption of fat. Orlistat blocks absorption of about 25% of the fat in a meal. The unabsorbed fat is excreted in the stool. |
| 3. | Orlistat is the saturated derivative of lipstatin, a potent natural inhibitor of pancreatic lipases isolated from the bacterium Streptomyces toxytricini. However, due to its relative simplicity and stability, orlistat was chosen over lipstatin for development as an anti-obesity drug. |
| 4. | Dietary fats need to be broken down into smaller pieces before the body can absorb them. Orlistat works by blocking the enzyme that breaks down fats in your diet. This undigested fat then passes out of your body in your bowel movement. |
| 5. | Orlistat does not block the absorption of calories from sugar and other non-fat foods, so you still need to restrict your total intake of calories. |
| 6. | Orlistat is notorious for its gastrointestinal side effects (sometimes referred to as treatment effects), which can include steatorrhea (oily, loose stools). In the United States and the European Union, orlistat is available for sale without a prescription. Generic formulations of orlistat are available in some countries |
Orlistat COA
| tems | Specification Items | Result |
| Appearance | white or almost white crystalline powder,smell less | White crystalline powder |
| Melting Point | 42.0~46.0°C | Confirmed |
| Specific Rotation | -31°~-39°(CHCl3,C=1) | Confirmed |
| Identification | The result of HPLC is consisitent to the reference one. The result of IR is consisitent to the reference one. | Confirmed |
| Related Substances | ≤ 0.5% | ≤ 0.05% |
| Total impurity | ≤ 1.0% | Confirmed |
| Single impurity | ≤ 0.1% | Confirmed |
| ≤ 290ppm | Confirmed | |
| ≤ 5000ppm | Confirmed | |
| Residual on Ignition | ≤0.1% | Confirmed |
| Sulphate | ≤ 0.05% | Confirmed |
| Heavy Metal | ≤ 20ppm | Confirmed |
| Purity | ≤ 99.0% ~ 99.9% | Confirmed |
